349931
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SKU
DD-IM-349931
| VDRC Id | 349931 |
|---|---|
| Library | DD-Im |
| Sub-Category | mutants |
| Status | available |
| Comment | BL32. A deletion removing the Defensin gene, first published in Parvy et al. (2019; eLife) having been backcrossed into the w[1118] DrosDel genetic background. A revisiting of this allele in Hanson et al. (2022; Proc R Soc B) later realized the Def[SK3]-containing chromosome had an alternate version of the Buletin allele, and so this was further isogenized to ensure the Buletin locus had an alanine allele matching the w[1118] DrosDel isogenic background, and the resulting strain published in Hanson et al. (2023; Dis Mod Mech). The correction of the Buletin allele to be alanine (matching the DrosDel background) affects the interpretation of Def[SK3] effects in previous literature pertaining to antibacterial defence in minor ways. |
| Construct Id | 349931 |
| Genotype | w[1118]; Def[SK3] |
| Gene Symbol | Def |
| Gene Name | Defensin |
| Synonyms | 143607_at AHA ATT ATTA Att Att A Att-A AttA AttC AttD AttaA Attacin Attacin A Attacin-A Attacin-A precursor Attacin-A AttacinA AttacinA Attackin BcDNA:LP05763 CecA-C DEF DIM 26 Def Defe |
| Keywords | DrosDel Immunity panel |
| Inserted Chromosome | 2 |
| Viability | viable |
| Publication | Hanson et al., eLife 8 (2019) |
| Provider Scientist | Bruno Lemaitre with the help of Mark Hanson |
| Provider Organization | EPFL |